Magnesium may ease hot flashesA pilot phase II trial of magnesium supplements to reduce menopausal hot flashes in breast cancer patients.
Study shows practical benefits.
We set out to explore whether magnesium could alleviate the uncomfortable hot flashes experienced by breast cancer patients. In our pilot study, we enrolled women who reported having at least 14 hot flashes a week and administered magnesium oxide. The dosage started at 400 mg for four weeks, and we allowed it to escalate to 800 mg if necessary.
Among the 29 women who joined, 25 completed the treatment, with an average age of 53.5 years. We found that the frequency of hot flashes decreased significantly, dropping from an average of 52.2 per week to 27.7, which is a 41.4% reduction. The overall hot flash score, which combines frequency and severity, also showed improvement, reducing by over 50%. More than half of the participants reported that their hot flashes had decreased by more than 50%, and nearly three-quarters experienced at least a 25% reduction.
Side effects were minimal, with only a couple of women discontinuing the treatment due to headache and nausea. Overall, compliance was excellent, and many participants chose to continue taking magnesium even after the study ended. As such, the results suggest that oral magnesium could be a promising option for managing hot flashes, encouraging further research through a randomized placebo-controlled trial.
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